oldschool flash开发人员什么时候应该使用flex？

What are the key differences between Flash and Flex? I have over five years experience with flash and feel very comfortable developing with it and ActionScript3. I find myself more and more curious about Flex and want to know when it is best to use flash or flex. Also, is everything that can be done with MXML, able to be done with AS3? I have a strong understanding of AS3 and OOP and would like to know the diffrences between using AS3 and MXML in Flex.What are the key differences between Flash and