如何在保存按钮单击时为复选框更改事件编写函数

I am having multiple checkboxes in a grid. Initially some checkboxes are checked and some are unchecked. Then i will change the checkbox selection and i want to save the changed checkbox values in to the database. When i reopen the page i will display the checkboxes checked with the saved values. I am having multiple checkboxes in a grid. Init