新表的索引策略 - SQL Server

What should be the index strategy to be followed when I am creating a brand new DB and/ or tables. As I will not have any user queries to analyse or requirements to find which column is being used mostly. What should be my index strategy/ (which columns should frame the clustered and which columns should participate in Non-Clustered)? How should I go ahead in this scenario?What should be the index strategy to be followe