I have an excel 2007 file(*.xlsx) which is to be opened through a python script. But the problem is I have two versions of MS office (2003 and 2007) installed in my computer. Although I tried to make Excel 2007 as the default application to open xlsx files, the win32com.client is trying to open my xlsx file using Excel 2003. Also this is reverting back Excel 2003 as the default application.I have an excel 2007 file(*.xlsx) which is to b