如何使用Regex.Replace一次替换两个字符串？

I have the following method that is replacing a "pound" sign from the file name but I want also to be able to replace the "single apostrophe ' " at the same time. How can I do it? This is the value of filename =Provider license_A'R_Ab#acus Settlements_1-11-09.xlsI have the following method that is replacing a