任何机构都知道msn首页开发人员使用的框架

I am now working on a huge site to developed it from scratch , but it should be light, fast , secure and optimize, for that i am looking to client side architecture, even the site is fully dynamic have millions of users and products. but still i want to use ajax , json and web services for quick response. But i am interesting to use client side archeticture like yahoo , google , and msn I am now working on a huge site to developed it