禁用特定接口的网络管理器

I would like to disable network manager service for particular interface(s). "/etc/init.d/NetworkManager stop" is not going to serve my purpose since will stop the service. Please let me know how to achieve this. Please suggest commands/code only - I am not interested in graphical configuration. If there is some rpm/patch available already please refer it to me. Can we configure network manager in such a way so that it will not detect any new network card plugged into the system?I would like to disable network manager service