将函数应用于列表列表的有效方法

I have 80 lists for the project in question. Each list is a list of length 1000. I'd like to run a function on each one (each of the 1000), and assign the results back to the original object. The total data is over 150 gigs so I want to make sure this is most efficient before running it on the actual data. Is this trivial example the best way to do what I need?I have 80 lists for the project in question. Ea