PYTHON：检查和编辑结构化数组中元素的最快方法是什么？

I have some issues with very large data sets. I need to find a solid and fast way to find/replace entries in my structured array. I am looking for an solution without looping of all entries. I know there are fast solutions for C but I do not know how to approach in python for that. I am also wonder if there is a numpy function for that very purpose!I have some issues with very large data sets. I